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Welcome to World Eye Cancer Hope

Retinoblastoma is an aggressive eye cancer affecting babies and young children.  It kills 7,000 youngsters each year, and blinds many more.

The most common early sign of childhood eye cancer is a white glow in the pupil of the affected eye.  The cancer is easy to diagnose and when treated early, is very curable.

Suffering and death is highest in developing countries, where most affected children live and timely access to specialist cancer care is limited.  In developed countries, cure is above 96%, but most children experience moderate, severe or complete vision loss.  Globally, children, families and survivors experience significant emotional trauma.

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In Your Country

WE C Hope for All Children with Eye Cancer, Families & Survivors.

Baby with one white pupil and one red pupilIncreasing access to specialist care will bring the promise of life and sight to every child, and improved life-long health to survivors. This is our mission. We:

  • Educate the public and medical community about retinoblastoma to achieve early diagnosis and rapid referral to specialist care
  • Empower medical teams to deliver sustainable high quality evidence-based care for affected children and adult survivors.
  • Enable family support programs that reduce practical and emotional burdens and improve access to essential care

One Rb World 2024 Conference Report

The 7th One Retinoblastoma World Conference took place October 15 – 17, 2024.  We were delighted to welcome 175 medical professionals, Rb patients, survivors of all ages, family members, and scientists to Honolulu, Hawaii, and many more online for three days of programming, community and collaboration in the heart of the Pacific.

One Rb World 2024 was hosted by World Eye Cancer Hope USA, organized together with Jesse Berry MD, Director of Ocular Oncology & Retinoblastoma at Children’s Hospital Los Angeles; Dr. Sandra Staffieri, Retinoblastoma Care Coordinator at the Royal Children’s Hospital Melbourne, Australia; and Maura Di Nicola MD, Assistant Professor of Clinical Ophthalmology at Bascom Palmer Eye Institute in Miami, Florida.

Our conference report showcases three days of diverse sessions, child life programming, community-building social events, and a plethora of feedback from attendees.  Please feel free to share, Mahalo nui loa!

Download the 2024 One Rb World Conference Report
Conference Report Cover. The top half features a lively group of around 60 people gathered in front of two trolley buses from E Noa Tours. Scenic mountains rise in the background. The group, diverse in age and background, is smiling, laughing, and making the friendly shaka hand sign. Many are wearing colorful leis, headbands, and sunglasses, adding to the joyful, celebratory vibe. The ONE RETINOBLASTOMA WORLD logo is prominently displayed, with black text and a stylized eye in a colourful circular design. Pink text below reads: HONOLULU, HAWAII, OCTOBER 15-17, 2024. In red text, the words: HOSTED BY WORLD EYE CANCER HOPE reflect WE C Hope branding. Finally, the words CONFERENCE REPORT are highlighted in blue. The bottom corners are decorated with vibrant pink and orange hibiscus flowers and green leaves.

Less Stress, More Success! Follow Our #RbChildLife Alphabet Of Hope

A child life specialist blows bubbles through an anesthesia mask towards a little girl

Caring for a child with retinoblastoma is so much more than treating the cancer. Child life focuses on the whole child – supporting their emotional, social, and developmental needs during stressful medical experiences, empowering families, and transforming care through education and play.

The #RbChildLife Alphabet of Hope highlights simple approaches and vital supports that help children with eye cancer and their families thrive during treatment and beyond.

Published every two weeks throughout 2025-6, each letter will be added to our website with links to further resources on the topic.  Visit the Alphabet Hub to get involved.

Discover the #RbChildLife Alphabet Of Hope

Save The Date! 8th One Rb World, 12-14 September, 2026 in San Antonio, Texas

Save the Date announcement for the One Rb World 2026 conference. A playful banner of brightly coloured squares spells out: SAVE THE DATE, over a vibrant night-time view of the San Antonio River Walk. Logo text reads: One Retinoblastoma World | San Antonio, Texas, September 12–14, 2026. Between the location and date, a small brick red quatrefoil outlined in white and clay pink features a sky blue horseshoe with white nail heads along the curve cupping a white lone star. The main conference logo features a target-like eye graphic with brightly coloured concentric rings surrounding a pearlescent circle, with a strand of DNA in the inner-most ring. In the background, festive San Antonio lights are strung across trees and buildings, all reflecting on the water. Colourful umbrellas and tables line the River Walk, evoking a cheerful, lively atmosphere.

Join patients, survivors, family members, medical professionals, and scientists for three days of programming, community and collaboration in the Lone Star State.

The 8th One Rb World Conference will take place before the 58th International Society of Paediatric Oncology (SIOP) World Congress, which will be held in San Antonio, 15-18 September 2026.

We recognize our 2026 conference falls during Rosh Hashanah, and we apologize for any conflicts this may create.  We hope many in our community will be able to participate, and we remain committed to making the conference as accessible and inclusive as possible.

You’ll find a very warm welcome with us in San Antonio, where we’ll advance patient-centred care and research for all together!

Find Out More About One Rb World

Stay up-to-date with WE C Hope’s eNewsletter!

A Glint or a Squint Could Be Your Hint of Eye Cancer!!

A baby boy looks at the camera. his right eye shows a white reflex while his left eye is turned in towards his nose.

Strabismus (turned eye) and leukocoria (white pupil), the most common signs of retinoblastoma, can also occur in healthy eyes

Being aware of these signs and seeking medical care early saves children’s lives and sight.

Prompt investigation of all signs and symptoms is vital to diagnose childhood eye cancer early. Timely diagnosis provides the best opportunity to save a child’s life and sight.

Discover the Signs & Symptoms

Buy WE C Hope Merch and More – Visit Our Store!

Nine panels feature eight different items available on World Eye Cancer Hope‘s TeePublic store, including a spiral bound notebook, a black running vest, a white tote bag, a red T-shirt, a mobile phone case, a green T-shirt, a white coffee mug, and a white long sleeve T-shirt with grey sleeves. In the centre panel, text reeds: “World Eye Cancer Hope merchandise now available at TeePublic. Along the bottom, text reeds use our unique link and a percentage of your purchase is donated to WE C Hope.

Wear your care for our retinoblastoma community with WE C Hope branded apparel, caps, bags, mugs, and much more. Buy exclusive gold ribbon designs, event-specific merch, and branded gear and gifts from for our fabulous partner, KnowTheGlow.

Help expand our range of designs, and sport your support for early diagnosis, patient-centred medical care, and support for all, for life!

Find Out More & Visit Our Store

Support Kids During Needle Related Procedures

Kenyan Child Life Specialist, Jayne Kamau, distracts a young patient with a meteor shower toy while a nurse inserts an IV in her hand.

Only 5% of children have support for immunization needle pain.

Seriously ill children experience many needle related procedures, rarely with adequate pain suppor.

Pain and distress can be managed and reduced.  IT DOESN’T HAVE TO HURT.

Parents, ask how to manage your child’s pain. Healthcare providers, please give parents options.

Learn how to make needles easier and safer for everyone.

Find Needle Supports for All Ages

WE C Hope Blog

Three young girls sit one behind the other as they enjoy riding together down a slide. The girl at the back has curly brown hair and wears a light pink sweater. The middle girl has blonde hair and wears a light purple shirt. The girl in front has light brown hair, wears a pink top, and holds a plaid cushion. They are surrounded by green foliage and trees in the background. The sun creates halos around their hair as it blows with their movement down the slide, and blue sky is seen in the top right corner, beyond the trees..

Bridging the Gaps: How Community and Shared Responsibility Create the Best Retinoblastoma Care

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Being the parent of a child with retinoblastoma, or living with the effects of this cancer every day, can be a frustrating experience. With an emphasis on our year-long theme of early diagnosis, we look at some of the challenges facing our retinoblastoma world, and for each, three ways we can work together to advance care for everyone.
A young African boy with short, curly black hair and a big, cheerful smile looks directly at the camera. He's wearing a cosy knitted blue sweater over a white collared shirt, and His right arm is flexed in a gesture of strength. The pupil of his right eye has a prominent pearly glow. Overlaying the wooden fence background, bold white text states "NO CHILD SHOULD DIE FROM UNDETECTED EYE CANCER." Below is a horizontal golden line. In the bottom left corner, the gold "KNOW THE GLOW®" logo is followed by the text "PREVENT CHILDHOOD BLINDNESS" in a smaller font. In the bottom right corner are the Kenyan flag and crests of the government and Kenyatta National Hospital, Nairobi.

Between Shadow and Light: Young Lives in Jeopardy from Retinoblastoma

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Worldwide, children and their families grapple with life-threatening eye cancer due to delayed diagnosis and care. Unchecked, retinoblastoma has far-reaching consequences. Through two family stories, WE C Hope CEO Abby White explores the impacts of low awareness, slow referral, and delayed care, and the life-saving, sight-saving opportunities they reveal.
Close up of a smiling, playful young African boy with a shaved head, who appears to be leaning against a tree. He has big, bright, happy eyes, one of which has a creamy glow in the pupil. He is wearing a light blue sweater. Across the blurred background, bold white text reads "HELP IDENTIFY CHILDHOOD EYE CANCER EARLY".

A Glint or a Squint Could Be Your Hint: Knowledge is Key to Retinoblastoma Early Diagnosis

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Critical clues to a child’s eye cancer hide in plain sight. Parent and physician knowledge, and ability to spot these silent signs are vital to early detection, swift referral, and prompt diagnosis. Meet five children from around the world whose parents’ curiosity, nagging concern, and action were pivotal to their diagnosis and life-saving, sight-saving care.
A diverse group of children and adults pose together, smiling and relaxed, in a spacious hanger-like room. Directly behind them is a large, conical-shaped boilerplate capsule spacecraft, displaying the words "Apollo Missions". To the left is a small, white aircraft with a clear bubble canopy. To the right, a sizable rocket engine or booster is mounted high up so its intricate pipes and nozzles can be viewed from below. In the far background, part of a dark blue wall displays celestial bodies.

Mile High Moments at the Denver Retinoblastoma Family Weekend

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Fifty retinoblastoma patients, survivors, and their family members joined World Eye Cancer Hope USA in February for three days of connection and fun in Colorado’s capital. Marissa D. Gonzalez, President and Founding Board Member or WE C Hope USA, shares highlights from the weekend, and why these gatherings are so important to our community.

Photographers

A baby has one red pupil and one white pupul - the classic early sign of eye cancer in children.

Know The Glow!

Learn about the most common early sign of childhood eye cancer – a white reflection in the pupil, seen in dim light and flash photos. Find out how to take photos to check for signs of serious eye disease in children.

FIND OUT MORE

Parents & Survivors

Sera is smiling as she holds up a large model eye in a space filled with greenery. She has medium-toned skin, her braided hair is decorated with small white beads, and she wears a long-sleeved light pink top.

Find Hope

We offer the Retinoblastoma Resource to supplement information provided by your medical team, answer questions and concerns about all aspects of life with Rb, increase understanding and share hope.

READ MORE

Family & Friends

How You Can Help

Forget “let me know if I can do anything to help”! Carefully considered and offered support will be truly valued.  We have many suggestions from parents that have brought families relief, joy and hope.

READ MORE

Give Hope

Sun reflects gold on Daisy's hair as she smiles and laughs while clutching a big bunch of daisies.

Help Change Lives!

There are so many ways you can help us bring hope of cure and better quality of life to children with eye cancer, families and survivors.  Donate online now, or become a fundraising angel. Together, WE C Hope!

FIND OUT MORE

We Are Proud to Be a Member of, and Partner With…

Know the Glow logo
International Society of Ocular Oncology logo
International Society of Paediatric Oncology logo
International Agency for the Prevention of Blindness Member logo

Help us bring hope of life and sight to every child with eye cancer

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