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Welcome to World Eye Cancer Hope

Retinoblastoma is an aggressive eye cancer affecting babies and young children.  It kills and blinds thousands every year.

The most common early signs of childhood eye cancer are a white glow in the pupil of the affected eye, and a turned or misaligned eye.  When diagnosed early and treated with expert care, this cancer is very curable.

Suffering and death is highest in developing countries, where most affected children live and timely access to specialist care is limited.  In developed countries, cure is above 96%, but most children experience moderate, severe or complete vision loss.  Globally, children, families and survivors experience significant emotional trauma.  Many survivors have lifelong treatment impacts and cancer risks, requiring specialist medical care.

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In Your Country

WE C Hope for All Children With Eye Cancer, Survivors, and Their Families

Baby with one white pupil and one red pupilIncreasing access to specialist care will save more children’s lives and sight, strengthen survivors’ lifelong health, and support family wellbeing.  We:

  • Educate the public and medical community about retinoblastoma to achieve early diagnosis and rapid referral to specialist care
  • Empower medical teams to deliver sustainable high quality evidence-based care for affected children and adult survivors.
  • Enable family support programs that reduce practical and emotional burdens and improve access to essential care

Less Stress, More Success! Follow Our #RbChildLife Alphabet Of Hope

A child life specialist blows bubbles through an anesthesia mask towards a little girl

Caring for a child with retinoblastoma is so much more than treating the cancer. Child life focuses on the whole child – supporting their emotional, social, and developmental needs during stressful medical experiences, empowering families, and transforming care through education and play.

The #RbChildLife Alphabet of Hope highlights simple approaches and vital supports that help children and their families thrive during treatment and beyond.

Every 4 weeks throughout 2025-6, a new letter will be added to our website with links to further resources on the topic.  Get involved at the Alphabet Hub.

Discover the #RbChildLife Alphabet Of Hope

Register Now! 8th One Rb World – Sep 12-14, 2026 – San Antonio, Texas

Register announcement for the One Rb World 2026 conference. A playful banner of brightly coloured squares spells out: REGISTER NOW, over a vibrant night-time view of the San Antonio River Walk. Logo text reads: One Retinoblastoma World | San Antonio, Texas, September 12–14, 2026. Between the location and date, a small brick red quatrefoil outlined in white and clay pink features a sky blue horseshoe with white nail heads along the curve cupping a white lone star. The main conference logo features a target-like eye graphic with brightly coloured concentric rings surrounding a pearlescent circle, with a strand of DNA in the inner-most ring. In the background, festive San Antonio lights are strung across trees and buildings, all reflecting on the water. Colourful umbrellas and tables line the River Walk, evoking a cheerful, lively atmosphere.

Join patients, survivors, family members, medical professionals, scientists, and advocates for 3 days of conversation, collaboration, and community in the Lone Star State.

One Rb World 2026 takes place before the 58th International Society of Paediatric Oncology World Congress, September 15-18, 2026 in San Antonio.

We recognize our 2026 conference falls during Rosh Hashanah, and we apologize for any conflicts this may create.  We hope many in our community will be able to participate, and remain committed to making the conference as accessible and inclusive as possible.

We welcome you warmly to One Rb World 2026 where we’ll advance patient-centred care and research for all together!

Register Now for One Rb World 2026!

Stay up-to-date with WE C Hope’s eNewsletter!

A Glint or a Squint Could Be Your Hint of Eye Cancer!!

A baby boy looks at the camera. his right eye shows a white reflex while his left eye is turned in towards his nose.

Strabismus (turned eye) and leukocoria (white pupil), the most common signs of retinoblastoma, can also occur in healthy eyes

Being aware of these signs and seeking medical care early saves children’s lives and sight.

Prompt investigation of all signs and symptoms is vital to diagnose childhood eye cancer early. Timely diagnosis provides the best opportunity to save a child’s life and sight.

Discover the Signs & Symptoms

Buy WE C Hope Merch and More – Visit Our Store!

Nine panels feature eight different items available on World Eye Cancer Hope‘s TeePublic store, including a spiral bound notebook, a black running vest, a white tote bag, a red T-shirt, a mobile phone case, a green T-shirt, a white coffee mug, and a white long sleeve T-shirt with grey sleeves. In the centre panel, text reeds: “World Eye Cancer Hope merchandise now available at TeePublic. Along the bottom, text reeds use our unique link and a percentage of your purchase is donated to WE C Hope.

Wear your care for our retinoblastoma community with WE C Hope branded apparel, caps, bags, mugs, and much more. Buy exclusive gold ribbon designs, event-specific merch, and branded gear and gifts from for our fabulous partner, KnowTheGlow.

Help expand our range of designs, and sport your support for early diagnosis, patient-centred medical care, and support for all, for life!

Find Out More & Visit Our Store

Support Kids During Needle Related Procedures

Kenyan Child Life Specialist, Jayne Kamau, distracts a young patient with a meteor shower toy while a nurse inserts an IV in her hand.

Only 5% of children have support for immunization needle pain.

Seriously ill children experience many needle related procedures, rarely with adequate pain suppor.

Pain and distress can be managed and reduced.  IT DOESN’T HAVE TO HURT.

Parents, ask how to manage your child’s pain. Healthcare providers, please give parents options.

Learn how to make needles easier and safer for everyone.

Find Needle Supports for All Ages

WE C Hope Blog

Two small group discussions are taking place around separate tables.

Ohana: The Beating Heart of One Retinoblastoma World 2024

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Though small and far-flung, our global retinoblastoma family stands strong together. Members of WE C Hope USA’s Board of Directors and past One Rb World participants explain how this conference unites us and strengthens ohana. In trial, grief, hope, and triumph, we share and learn from our collective experience, support one another, and strive to care for all.
Close-up image of a young African child wearing a cartoon pattern t-shirt, looking directly at the camera. The child's left eye has a noticeable white glow. Over the softly focused background, white text reads What if their eye is telling you something? Below a horizontal golden line is the gold KNOW THE GLOW® logo and the text PREVENT CHILDHOOD BLINDNESS. In the bottom right corner are the Kenyan flag and crests of the government and Kenyatta National Hospital, Nairobi.

Gut Feelings Matter: How Parent Instinct and Intuition Detect Childhood Eye Cancer Early

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Strong parent instinct and intuition often lead to a child’s eye cancer diagnosis. Rb Survivor and WE C Hope CEO, Abby White explores what they are and how they differ, why they are so important for retinoblastoma early detection, why primary care providers should take them seriously, and how they impacted the diagnosis journey of four children.
Close-up of a young African boy smiling broadly. He has short hair and wears a blue tank top. The background is blurred with warm, earthy tones. Overlaying text reads: A photo can identify cancer in a child’s eye. Below a horizontal golden line is the gold KNOW THE GLOW® logo and the text PREVENT CHILDHOOD BLINDNESS. In the bottom right corner are the Kenyan flag and crests of the government and Kenyatta National Hospital, Nairobi.

Pearls of Light: The Pathway to Retinoblastoma Early Detection

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Early diagnosis of retinoblastoma saves children’s lives, and offers the best opportunity for safe vision saving therapy. But worldwide, many children are diagnosed late. KnowTheGlow founder, Megan Webber, and WE C Hope USA President, Marissa D. Gonzalez discuss how our early detection partnership evolved, and update on the progress we’re making for children in Africa and Asia.
A large, diverse group of people pose together in a conference room. Most are dressed in smart casual attire. Many are smiling and waving at the camera, and those in the centre are holding a large banner that reads "One Retinoblastoma World". A large world map features on the wall behind the group. At the front, two ladies sit close together holding a plush elephant with removable eye between them. The elephant is bedecked in red, white and blue flowers.

Laulima: Many Hands, One Retinoblastoma World

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Laulima signifies the power of cooperation, teamwork and collective effort.  This Hawaiian concept of many hands striving together drives the One Rb World conference, taking place in Honolulu this October.  Members of our 2024 conference team explain how laulima inspires their work for this global community, united to advance retinoblastoma care for all.

Photographers

A baby has one red pupil and one white pupul - the classic early sign of eye cancer in children.

Know The Glow!

Learn about the most common early sign of childhood eye cancer – a white reflection in the pupil, seen in dim light and flash photos. Find out how to take photos to check for signs of serious eye disease in children.

FIND OUT MORE

Parents & Survivors

Sera is smiling as she holds up a large model eye in a space filled with greenery. She has medium-toned skin, her braided hair is decorated with small white beads, and she wears a long-sleeved light pink top.

Find Hope

We offer the Retinoblastoma Resource to supplement information provided by your medical team, answer questions and concerns about all aspects of life with Rb, increase understanding and share hope.

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Family & Friends

How You Can Help

Forget “let me know if I can do anything to help”! Carefully considered and offered support will be truly valued.  We have many suggestions from parents that have brought families relief, joy and hope.

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Give Hope

Sun reflects gold on Daisy's hair as she smiles and laughs while clutching a big bunch of daisies.

Help Change Lives!

There are so many ways you can help us bring hope of cure and better quality of life to children with eye cancer, families and survivors.  Donate online now, or become a fundraising angel. Together, WE C Hope!

FIND OUT MORE

We Are Proud to Be a Member of, and Partner With…

Know the Glow logo
International Society of Ocular Oncology logo
International Society of Paediatric Oncology logo
International Agency for the Prevention of Blindness Member logo

Help us bring hope of life and sight to every child with eye cancer

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