Retinoblastoma can spread beyond the eye when it is not diagnosed promptly and treated appropriately by an experienced doctor. This is called extraocular or metastatic retinoblastoma.
Delaying recommended eye removal surgery puts the child’s life at serious risk, and is the second most common cause of extraocular retinoblastoma and death after delayed diagnosis.
There are three ways retinoblastoma can spread outside the eye.
Risk factors include:
Tumour spread beyond the eye is very common in resource-limited regions of the world, where diagnosis is often delayed, and treatment Is difficult.
Though rare in developed countries, extraocular relapse has become more common in recent years due to increased efforts to save severely affected eyes.