Several days after high dose chemotherapy, the stem cells or marrow is returned as an intravenous infusion, similar to a blood transfusion.
The stem cells or marrow find their way to the bone cavities and begin to produce new, healthy blood cells. This is why transplants are sometimes called “stem cell / bone marrow rescue”.
Sometimes, several rounds of high-dose chemotherapy are given with stem cell rescue after each round. This is called tandem or serial transplant.