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Welcome to World Eye Cancer Hope

Retinoblastoma is an aggressive eye cancer affecting babies and young children.  It kills 7,000 youngsters each year, and blinds many more.

The most common early sign of childhood eye cancer is a white glow in the pupil of the affected eye.  The cancer is easy to diagnose and when treated early, is very curable.

Suffering and death is highest in developing countries, where most affected children live and timely access to specialist cancer care is limited.  In developed countries, cure is above 96%, but most children experience moderate, severe or complete vision loss.  Globally, children, families and survivors experience significant emotional trauma.

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In Your Country

WE C Hope for All Children with Eye Cancer, Families & Survivors.

Baby with one white pupil and one red pupilIncreasing access to specialist care will bring the promise of life and sight to every child, and improved life-long health to survivors. This is our mission. We:

  • Educate the public and medical community about retinoblastoma to achieve early diagnosis and rapid referral to specialist care
  • Empower medical teams to deliver sustainable high quality evidence-based care for affected children and adult survivors.
  • Enable family support programs that reduce practical and emotional burdens and improve access to essential care

One Rb World 2024 Conference Report

The 7th One Retinoblastoma World Conference took place October 15 – 17, 2024.  We were delighted to welcome 175 medical professionals, Rb patients, survivors of all ages, family members, and scientists to Honolulu, Hawaii, and many more online for three days of programming, community and collaboration in the heart of the Pacific.

One Rb World 2024 was hosted by World Eye Cancer Hope USA, organized together with Jesse Berry MD, Director of Ocular Oncology & Retinoblastoma at Children’s Hospital Los Angeles; Dr. Sandra Staffieri, Retinoblastoma Care Coordinator at the Royal Children’s Hospital Melbourne, Australia; and Maura Di Nicola MD, Assistant Professor of Clinical Ophthalmology at Bascom Palmer Eye Institute in Miami, Florida.

Our conference report showcases three days of diverse sessions, child life programming, community-building social events, and a plethora of feedback from attendees.  Please feel free to share, Mahalo nui loa!

Download the 2024 One Rb World Conference Report
Conference Report Cover. The top half features a lively group of around 60 people gathered in front of two trolley buses from E Noa Tours. Scenic mountains rise in the background. The group, diverse in age and background, is smiling, laughing, and making the friendly shaka hand sign. Many are wearing colorful leis, headbands, and sunglasses, adding to the joyful, celebratory vibe. The ONE RETINOBLASTOMA WORLD logo is prominently displayed, with black text and a stylized eye in a colourful circular design. Pink text below reads: HONOLULU, HAWAII, OCTOBER 15-17, 2024. In red text, the words: HOSTED BY WORLD EYE CANCER HOPE reflect WE C Hope branding. Finally, the words CONFERENCE REPORT are highlighted in blue. The bottom corners are decorated with vibrant pink and orange hibiscus flowers and green leaves.

Less Stress, More Success! Follow Our #RbChildLife Alphabet Of Hope

A child life specialist blows bubbles through an anesthesia mask towards a little girl

Caring for a child with retinoblastoma is so much more than treating the cancer. Child life focuses on the whole child – supporting their emotional, social, and developmental needs during stressful medical experiences, empowering families, and transforming care through education and play.

The #RbChildLife Alphabet of Hope highlights simple approaches and vital supports that help children with eye cancer and their families thrive during treatment and beyond.

Published every two weeks throughout 2025-6, each letter will be added to our website with links to further resources on the topic.  Visit the Alphabet Hub to get involved.

Discover the #RbChildLife Alphabet Of Hope

Save The Date! 8th One Rb World, 12-14 September, 2026 in San Antonio, Texas

Save the Date announcement for the One Rb World 2026 conference. A playful banner of brightly coloured squares spells out: SAVE THE DATE, over a vibrant night-time view of the San Antonio River Walk. Logo text reads: One Retinoblastoma World | San Antonio, Texas, September 12–14, 2026. Between the location and date, a small brick red quatrefoil outlined in white and clay pink features a sky blue horseshoe with white nail heads along the curve cupping a white lone star. The main conference logo features a target-like eye graphic with brightly coloured concentric rings surrounding a pearlescent circle, with a strand of DNA in the inner-most ring. In the background, festive San Antonio lights are strung across trees and buildings, all reflecting on the water. Colourful umbrellas and tables line the River Walk, evoking a cheerful, lively atmosphere.

Join patients, survivors, family members, medical professionals, and scientists for three days of programming, community and collaboration in the Lone Star State.

The 8th One Rb World Conference will take place before the 58th International Society of Paediatric Oncology (SIOP) World Congress, which will be held in San Antonio, 15-18 September 2026.

We recognize our 2026 conference falls during Rosh Hashanah, and we apologize for any conflicts this may create.  We hope many in our community will be able to participate, and we remain committed to making the conference as accessible and inclusive as possible.

You’ll find a very warm welcome with us in San Antonio, where we’ll advance patient-centred care and research for all together!

Find Out More About One Rb World

Stay up-to-date with WE C Hope’s eNewsletter!

A Glint or a Squint Could Be Your Hint of Eye Cancer!!

A baby boy looks at the camera. his right eye shows a white reflex while his left eye is turned in towards his nose.

Strabismus (turned eye) and leukocoria (white pupil), the most common signs of retinoblastoma, can also occur in healthy eyes

Being aware of these signs and seeking medical care early saves children’s lives and sight.

Prompt investigation of all signs and symptoms is vital to diagnose childhood eye cancer early. Timely diagnosis provides the best opportunity to save a child’s life and sight.

Discover the Signs & Symptoms

Buy WE C Hope Merch and More – Visit Our Store!

Nine panels feature eight different items available on World Eye Cancer Hope‘s TeePublic store, including a spiral bound notebook, a black running vest, a white tote bag, a red T-shirt, a mobile phone case, a green T-shirt, a white coffee mug, and a white long sleeve T-shirt with grey sleeves. In the centre panel, text reeds: “World Eye Cancer Hope merchandise now available at TeePublic. Along the bottom, text reeds use our unique link and a percentage of your purchase is donated to WE C Hope.

Wear your care for our retinoblastoma community with WE C Hope branded apparel, caps, bags, mugs, and much more. Buy exclusive gold ribbon designs, event-specific merch, and branded gear and gifts from for our fabulous partner, KnowTheGlow.

Help expand our range of designs, and sport your support for early diagnosis, patient-centred medical care, and support for all, for life!

Find Out More & Visit Our Store

Support Kids During Needle Related Procedures

Kenyan Child Life Specialist, Jayne Kamau, distracts a young patient with a meteor shower toy while a nurse inserts an IV in her hand.

Only 5% of children have support for immunization needle pain.

Seriously ill children experience many needle related procedures, rarely with adequate pain suppor.

Pain and distress can be managed and reduced.  IT DOESN’T HAVE TO HURT.

Parents, ask how to manage your child’s pain. Healthcare providers, please give parents options.

Learn how to make needles easier and safer for everyone.

Find Needle Supports for All Ages

WE C Hope Blog

Pamela Paul stands at a light wooden podium against a black background. She wears a blue dress patterned with yellow, pink, and orange flowers.

Storytelling for Life: Global Solutions and Lifelong Care at One Rb World 2024 Day Three | Page 3

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As the 7th One Rb World Conference in Honolulu, Hawaii, reached its final hours, personal insights and global initiatives took center stage. Marissa D. Gonzalez, President of World Eye Cancer Hope USA, and Conference Event Chair, reflects on the collective mission to save lives, including The New York Times Opinion feature, “It Takes a Lifetime to Survive Childhood Cancer,” – and the story behind the article.
Mark sits at a round table covered in a white tablecloth, He wears a black t-shirt and black glasses, and holds baby Lennox on his lap. Lennox wears a white t-shirt with green sleeves. A woman seated close by is smiling as she watches them together.

From Treatment to Triumph: Seeking Cure for All at One Rb World 2024 Day Three | Page 2

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Day Three of the 7th One Rb World Conference in Honolulu, Hawaii, continued to inspire with an in-depth exploration of treatment pathways, survivor resilience, and global efforts to save lives. Marissa D. Gonzalez, President of World Eye Cancer Hope USA, and Conference Event Chair, shares highlights from the vital discussions and profound personal stories shaping a hopeful future for all affected by retinoblastoma.
10 adults smile together in front of a sign reading “Mahalo! One Retinoblastoma World”. Peggy and Michael are wearing black long-sleeve tops with dark wash jeans. Kirsten Ramos wears a blue shirt with light wash jeans. Jesse Berry wears a green dress with ruffles around the collar. Cat Paul and Joe Cox are wearing aqua-blue One Retinoblastoma World 2024 t-shirts featuring the conference logo and a design with palm trees, hibiscus, and waves. Victoria Danhakl wears a yellow and brown floral dress. And Roselle and Josh Castanon wear shirts with the slogan: I wear gold to support my daughter.

A Global Call to Action: Early Detection and Advocacy at One Rb World 2024 Day Three | Page 1

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Day Three of the 7th One Rb World Conference in Honolulu, Hawaii, was a powerful culmination of global community, collaboration, and hope. From early detection in rural communities to life-saving care, from child life to patient-led research, and more. Marissa D. Gonzalez, Conference Event Chair, shares highlights from the inspiring presentations, life-changing progress, and extraordinary stories that closed this remarkable event.
Grace stands in front of a Hawaiian-themed backdrop of lush green foliage, flowers, fairy lights, and the word Aloha written in a glittery gold cursive font. She wears a beautiful floral dress in shades of pale pink, orange, and white. Her conference lanyard clearly shows her name badge, reading Grace Mbugua. She smiles broadly and holds a sign in each hand – one says: World Eye Cancer Hope - life and sight for every child. The other says: One Retinoblastoma World, Honolulu, Hawaii, October 15-17, 2024.

One Rb World 2024 Shines the Light on Life-Saving Care: Highlights from Hawaii Day Two | Page 2

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Continuing our review of Day Two at the 7th One Rb World Conference in Honolulu, Hawaii, we explore critical life-saving advancements in global retinoblastoma care. Marissa D. Gonzalez, President of World Eye Cancer Hope USA, and Conference Event Chair, delves deeper into the research developments, technological breakthroughs, collaborations, joyful child life, and uplifting survivor stories shaping a brighter future for all.

Photographers

A baby has one red pupil and one white pupul - the classic early sign of eye cancer in children.

Know The Glow!

Learn about the most common early sign of childhood eye cancer – a white reflection in the pupil, seen in dim light and flash photos. Find out how to take photos to check for signs of serious eye disease in children.

FIND OUT MORE

Parents & Survivors

Sera is smiling as she holds up a large model eye in a space filled with greenery. She has medium-toned skin, her braided hair is decorated with small white beads, and she wears a long-sleeved light pink top.

Find Hope

We offer the Retinoblastoma Resource to supplement information provided by your medical team, answer questions and concerns about all aspects of life with Rb, increase understanding and share hope.

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Family & Friends

How You Can Help

Forget “let me know if I can do anything to help”! Carefully considered and offered support will be truly valued.  We have many suggestions from parents that have brought families relief, joy and hope.

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Give Hope

Sun reflects gold on Daisy's hair as she smiles and laughs while clutching a big bunch of daisies.

Help Change Lives!

There are so many ways you can help us bring hope of cure and better quality of life to children with eye cancer, families and survivors.  Donate online now, or become a fundraising angel. Together, WE C Hope!

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We Are Proud to Be a Member of, and Partner With…

Know the Glow logo
International Society of Ocular Oncology logo
International Society of Paediatric Oncology logo
International Agency for the Prevention of Blindness Member logo

Help us bring hope of life and sight to every child with eye cancer

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