The Hyatt Regency sits on the San Antonio River Walk.
Hyatt Regency San Antonio River Walk
All One Rb World conference sessions will take place at the
Hyatt Regency San Antonio River Walk
123 Losoya Street
San Antonio, Texas 78205
United States
Phone: +1 (210) 222-1234
Location
Centrally located on the city’s vibrant River Walk, with direct access to the historic Alamo, our San Antonio hotel places you in the heart of downtown’s entertainment, culture, and historic center.
Distance from the SIOP Congress venue (the Henry B. González Convention Center): 5 minute drive, 6 minute bike ride, 5-9 minute walk along the beautiful River Walk.
Guest Rooms
All guest rooms include: air conditioning, free Wi-Fi, blackout curtains, mini-fridge, coffee maker, in-room safe, hair dryer, iron and ironing board, and a flat-screen TV with Chromecast.
Hotel Amenities
Hotel facilities include: business services, laundry, concierge, fitness center, rooftop pool, spa, on-site restaurant and bar, and mobile app for convenient dining anywhere in the hotel.
Airport Transportation
The Hyatt Regency is 8 miles from San Antonio International Airport (SAT), or a short drive. The hotel does not offer an airport shuttle, and suggests taking a taxi or rideshare from the airport.
Parking
Parking and electric vehicle charging are available at the hotel. Parking rates are:
- Overnight self-parking: $47.
- Standard valet: $59
- Oversized valet: $69.
Conference Guest Rooms
A number of Hyatt Regency San Antonio River Walk guestrooms are available to our meeting participants at a special delegate rate:
- Single and Double rates are $219 per night.
- Triple rate is $244 per night.
- Quad rate is $269 per night.
- There is no additional charge for children under the age of 18. The Triple and Quad room pricing only applies to additional adult guests.
- Available from Thursday September 10, 2026 to Thursday September 17, 2026.
- A selection of king beds, 2 queen beds, and larger suites are available to book (subject to availability).
- All rooms are subject to 16.75% OT tax and 1.25% TPID tax, as well as a $2.54 SCRF hotel fee per night.
Click here to book at our discounted event rate
Discover more about the Hyatt Regency San Antonio River Walk
Book Your Stay
Please follow the specific booking instructions below to benefit from our special group rate:
- Book by Thursday August 27, 2026.
- Click here to book online using our group booking portal
- If you prefer to make your reservation by phone, call the group reservations team at (402)593-5132 and quote One Retinoblastoma World once the rooms are available in December 2025.
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